Mauricio Pellegrino was heartened by the atmosphere created by the Saints fans at St Mary's last weekend and is hoping for a repeat this Saturday.
Southampton host West Ham United, as they look to build on their opening-day draw with Swansea City, and a full house is again expected for the match.
Pellegrino has been buoyed by the backing of the club's supporters since he arrived, including in last Saturday's season opener, and he believes they can play a big part again tomorrow.
"Hopefully we can keep going and keep playing in the same way," he said. "I think we are on the right track and the people were the other day behind the team and pushing us.
"We know that it will be a really difficult game, but together – the players and the fans – we have to be as a unit to try to win the game."
West Ham have been busy this summer in the transfer market, signing players such as Joe Hart, Javier Hernandez and Marko Arnautović, and Pellegrino is expecting a stern test from them.
"We never know what will happen," he said, when asked what sort of an approach he anticipated from the Hammers.
"Football is an unpredictable game, but they signed important players, with experience in the Premier League, with the capacity to create problems. In parallel, I think we are ready to keep going and do a good performance."