Saints duo Dušan Tadić and Manolo Gabbiadini are both set for international action for their respective nations today.
Tadić will be hoping to continue his scintillating form in World Cup qualifying for Serbia when they host Wales in Group D at Crvena Zvezda Stadium (7.45pm BST).
The diminutive playmaker has been key in helping his country to top spot in the standings, after scoring four goals and setting up seven of their 12 goals.
Elsewhere, Manolo Gabbiadini is in the Italy squad that will take on Liechtenstein at Udinese’s Dacia Arena in a 7.45pm kick-off.
Gabbiadini came off the bench late on in the 3-0 friendly win over Uruguay on Wednesday, making an immediate impact when he assisted Éder.
Giampiero Ventura’s side are second only to Spain in Group G, with both sides on 13 points from five games.