Claude Puel has hailed the ‘fantastic support’ for his side ahead of their Group K fixture against Internazionale on Thursday night.
Saints will be backed by 6,715 supporters at the San Siro, as they look to tighten their grip on top spot in the UEFA Europa League.
And Puel hopes to reward the travelling fans with a memorable victory, as he delivered a message to them at his pre-match press conference.
He said: “I hope they take pleasure to see this stadium and I hope for a very good game between two good teams with good spirit and good football, because they like to play good football.
“We will see the result but it will be important to give a good message for all the team and for all of our fans.
“I think it is fantastic support and it’s important to continue this good relation with our fans.”
The San Siro has been a place where Puel himself has experienced mixed fortunes.
He was a part of the AS Monaco side, then under the stewardship of Arsene Wenger, that were beaten 3-0 in the Champions League semi-final by AC Milan in 1994, but he is looking for win number two there as a manager.
Puel explained: “I come in this stadium one time as player and it was not a good thing against Milan in the semi-final of the Champions League, and a good thing the second time with Lille and we win here.
“For the third time, I hope for a good result and to take pleasure in seeing my team play good football.”