Claude Puel says he is likely to make changes again for the visit of Swansea City, following the Europa League win over Sparta Praha.
The Saints boss made seven alterations to the side that lost to Arsenal for the visit of the Czech club on Thursday, with his team going on to win 3-0.
However, with such a short turnaround between matches, Puel confirmed he will consider making changes again this weekend.
"We could see against Prague the possibilities to change many players from the game against Arsenal," the Saints boss told youtube.com/southamptonfc.
"I think it's important for the players and for the squad to see all the players put in good work.
"It's important to keep good quality on the play and, of course, good results.
"I think this game against Sparta was very important for the result, of course, but also for the confidence of the team and the squad, and for the future we can bring energy and quality with these young players."
Puel said he had no new injury concerns following the win over Sparta, although he did reveal that Jay Rodriguez will be assessed for a minor issue.
"We just have to see about Jay, who has felt something, but it's nothing major," said Puel. "We will see on him."